[ikk157]

Agreed @rudra, and that's exactly my point. If no one volunteers to take a dose of the vaccine, clinical trial will never be possible. And I can give a signed guarantee that even if I was of the requisite age I wouldn't have been allowed to volunteer either.

@ikk157 Well yeah your opinion and viewpoint is quite radical, after all you're gonna risk your life even if slightly to let your body be experimented upon with a vaccine that's purely untested. But again, as I said someone will have to volunteer to get this vaccine a clean sheet, and henceforth public benefit at large.

Now I'd like to ask something else at this point, well, as far as I knew, these clinical trials were only to test if the body produces the requisite antigens and antibodies to fight against the virus, and further to see that there are no unwanted and alarming side effects. I don't think there was a mention of infecting you with COVID and getting this tested. This is a vaccine and not a medicine, I think the latter is what you're talking about. In that case, of course the medicine that passes intal trials would be administered to volunteer (already infected) patients from various places.

But then if you’re not infected with the virus, technically the body won’t produce the antibodies (because why would it?)... so testing the vaccines effectiveness might not yield reliable results. Sure vaccines tend to be a weakened pathogen to give the body time to identify how to fight it, hence when the real thing strikes the body knows exactly what to do. However, even if the body does produce antibodies for the weakened virus, there’s no guarantee that this will work on the real deal unless you actually test it.

But this is in theory of course... I don’t really know how they test its effectiveness in these trials. If it’s the method you described, then, yet again, it might not yield reliable results.

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@HostSlick
omg ! none is paying even a dime here for this. I think I should keep Germany in my list of countries to emigrate to then.

@ikk157 @sohamb03

Thanks .. i would like to take this opportunity to clarify some things...

1) Search ' genetic chimera' in Google. There are people like that. also remember that from count of living cells in your body, more than half of the cells that make you are not yours or contain your genetic code. what we are is a joint effort of many. you really need the colonies / microbes living in your guts, skin, orifices , tracts. you need them. without them, you will have to live locked up in a artificially made very sterile environment.
so getting some live but attenuated ( non damaging) or dead virus or some protein (s) / chemical parts from them is not going to harm you in any significant and lasting way.

2) those rumors about vaccine test killing subjects is just bull crap. they test their safety on animal models first.

At worst what you might get is severe fever or / and some other symptoms. all these will clear up within months, if not weeks.

3) vaccines trigger matching immune response before the real threat gets in your body. so body gets time to prepare. that is triggering production of antibody.

antigen is what gets in and triggers .... the harmful things. so vaccine mimics antigen to trigger response ....

4) i hear they are going even more direct than this... they are taking samples from people who didnt even show much symptoms after getting infected and finding the antibodies in them and cloning those and going to use these super powered antibody doses on those who could not produce that kind of response ...or did but weak ones... this technology is already being used in case of ebola and cancer (pancreatic cancer ) etc i think.

so what this means is, we dont produce same kind of antibody when exposed to the same antigen. it is like calling the seal team to fight for you..

vaccines get used on healthy bodies ...i dont see what could be the point of using vaccines on someone already ill. the invading pathogen is already inducing the immune response. but these cloned antibody doses are used after you are ill. so there is that...

5) you dont need to get infected to test the viability of the vaccines. stage one trial ensures safety... in later stages they work to detect effect and effectiveness and doses etc .. so they just take blood samples and detect whether enough number of antibodies are being generated in your body by using laboratory tests. you dont need to get infected for that..

one can use live testing ....it has slight speed advantage. but due to high risk...not used usually..

FINALLY

Did you know that Isaac Newton used to prod inside his eyes using a needle so he could understand how eyes worked etc....i know that is a very high bar for dedication to science. but scientists are a mad bunch ...lol

SO IF YOU BELIEVE IN THE AUTHORITY OR THE PEOPLE WORKING ON THE VACCINE TO NOT LIE AND BE RESPONSIBLE, THEN PLEASE JOIN THEIR TRIALS...

I’d like to comment on your point of testing the vaccines safety on animals:

While this is a great step in figuring out how safe the vaccines are, it’s not really that great of an indication. As everyone knows, animal’s bodies tend to behave very differently from human beings in many aspects. So just because a vaccine proves itself safe in animals won’t necessarily mean it’s actually safe on humans. The risk is still there!

As for you calling the deaths caused by the trials rumors, would you mind pointing us to the source of that?

And for your point in the way they test the viruses effectiveness, please refer to my response to @sohamb03’s post.

But the remainder of your points are quite reasonable and I fully agree on those!